Effect Modification of Inorganic Arsenic

Studies suggest that inorganic arsenic (iAs), a known environmental toxicant, may increase the risk of diabetes. Conversely, researchers have observed an inverse relationship between vitamin D and glycohemoglobin, a biomarker of diabetes mellitus. This study examined whether iAs modifies the association between vitamin D and dysglycemia among U.S adults. Although prior research has explored the relationship between vitamin D and glycohemoglobin, the role of environmental factors, such as arsenic, remains understudied. Understanding how arsenic affects the association may extend current knowledge of vitamin D’s protective role and provide context in which vitamin D is most effective, potentially informing more effective preventive strategies. This cross-sectional analysis used 2009-2014 data from the National Health and Nutrition Examination Survey (NHANES) database…

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